argatroban dosing calculator
Infusion Rate Calculator Use the tab key to navigate the form. Argatroban or heparin were administered as adjunctive therapy to alteplase and adjusted to.
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Maximum dose 10mcgkgmin Switching to warfarin.
. 12 mcgkgmin for non-hepatically compromised patients. This program allows for multiple selections. 100 mcgkg iv bolus followed by either low-dose 1 mcgkgminute continuous iv infusion or high-dose 3 mcgkgminute continuous iv infusion argatroban was compared to heparin 70 unitskg iv bolus followed by 15 unitskghour continuous iv infusion.
Obtain an activated clotting time ACT 5 to 10 minutes after the bolus dose is completed. Select Drug and Concentration For medications that are renal adjusted argatroban Angiomax bivalirudin Integrilin milrinone you may use the creatinine clearance calculator. Standard Argatroban Infusion is 250mg in Normal Saline 250mL yielding a concentration of 1 mgmL or 1000 mcgmL.
Therefore obese patients actual body weight 120 of IBW require a correction in the weight used for V d calculation and dose. Argatroban interferes with the INR assay. Required data entry fields are teal in color.
Adult amikacin traditional dosing calculator is based on a calculation method proposed by Sarubbi and Hull. Adjust dose until the steady-state aPTT is 15 to 3 times the initial baseline value. To calculate INR for warfarin alone INR W based on INR for co-therapy of warfarin and Argatroban INR WA when the Argatroban dose is 2 mcgkgmin use the equation next to the appropriate curve.
Check an activated clotting time ACT 5 to 10 minutes after the bolus dose is completed. A bolus of 350 mcgkg IV over 3-5 minutes via large-bore IV line Check activated clotting time ACT 5-10 minutes after bolus dose is completed. Measure aPTT after 2 hours.
Argatroban dose 2 mcgkgmin Argatroban dose 2 mcgkgmin INR 4 1. 075 mcgkgminute by continuous IV infusion. Obtain ACTs before dosing 5 to 10 minutes after bolus dosing following adjustments in the infusion rate and at the end of the PCI procedure.
Other fields are output only. Hepatic Disease Score Calculator for Argatroban Dosing. Consider increase in the dose while Argatroban 2.
Thanks for using the program. Follow instructions in the column to the right A-D starting that same day. Formula Composition Depending on units selected the.
2 OR 4 for patients with primary biliary cirrhosis 1 point 2-3 OR 4-10 for patients with primary biliary cirrhosis 2 points 3 OR 10 for patients with primary biliary cirrhosis 3 points Albumin gdl. It is a useful tool to determine the rate of pump medication infusion to achieve therapeutic dosing. If you hold down the shift key you can select an entire range of drugs for example you can click on the first drug in the list and then while holding the shift key select the last drug and you will notice that the.
Based on these results argatroban should be dosed using actual body weight regardless of BMI. See the Argatroban Adjustment Dosing Calculator. Please seek haematology advice if necessary.
The PCI procedure may proceed if the ACT is greater than 300 seconds. Argatroban should be continued as bridging therapy with oral anticoagulation of the coumarin type for a. You will find a medical calculator for BMI clinical calculator for creatinine clearance metric to english conversion and more.
Select a practical dosage and interval. Stopping this drug too early could result in a lapse in therapeutic anticoagulation. The dose for heparin-induced thrombocytopenia without hepatic impairment is 2 mcgkgmin administered as a continuous infusion 21 Discontinue heparin therapy and obtain a baseline aPTT before administering Argatroban 21 After the initial dose of Argatroban the dose can be adjusted as clinically indicated 21.
And even over 20 financial calculators related to retirement savings investments mortgages and loans. Choose practical convenient doses and administration schedules. Obtain hematology consultation regarding Warfarin management INR 4 1.
05 mcgkgmin for patients with CHF mild hepatic insufficiency and critical illness. Argatroban dosing in obesity Obese patients require similar median argatroban maintenance doses when compared to non-obese patients. If argatroban therapy is used concurrently with or following FFP or a thrombolytic some centers decrease dose by half.
Odd doses and schedules may lead to errors in administration Round dosing interval up to the nearest 6 8 12 or 24 hours Round aminoglycoside doses to the 10 mg increment. Therapeutic Goal Range for PTT is 55-100. Co-administered with Argatroban at a dose of 2 mcgkgmin.
Check peak and trough with 3 rd or 4 th dose. To pick and choose one drug at a time hold down the ctrl key and make as many selections as you need. Obese patients require similar median argatroban maintenance doses when compared to non-obese patients.
Procedure may proceed if ACT is 300 seconds If ACT. Aminoglycosides distribute very poorly into adipose tissue. Doses 2 mcgkgmin Temporarily reduce dose of argatroban to 2 mcgkgmin in order to predict INR on warfarin alone Repeat INR 4 to 6 hours after reduction and follow the process outlined for doses up to 2 mcgkgmin This is to be used as a guide and.
Argatroban injection prescribing information Sandoz 0516. Reduce Argatroban dose to 2 mcgkgmin regardless of PTT 2. Obtain additional ACTs every 20 to 30 minutes during a prolonged procedure.
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